Botox in Piscataway, NJ

The earliest settlers of the area were the Lenape Native Americans; a group of four European settlers coming from New Hampshire acquired 40,000 acres (16,000 ha) of land in 1666 that had been occupied by Native Americans.

In 1666, the first proprietary Governor of the Province of New Jersey, Philip Carteret, granted 12 new settlers from Massachusetts a 100 square mile allotment of land that was later founded as the townships of Piscataway and Woodbridge. Similar types of settlements established by religious dissenters fleeing Puritan colonies in New England were being formed in other parts of New Jersey, notably the Elizabethtown Tract in Northern New Jersey near the mouth of the Raritan River and extending upwards into modern day Essex County, and the Monmouth Tract in Central New Jersey near the Raritan Bay and extending southward along the Jersey Shore to the Barnegat Inlet.

Additional settlers from the Piscataqua River area of New Hampshire moved to Piscataway, bringing the name. Coming from a lumbering, shipbuilding and fishing background, these settlers, consisting of mostly Baptists and Quakers, were comfortable with their new surroundings, and looking forward to starting a new life away from political and religious persecution in the north. They were also enterprising and pioneering families who were already experienced in wilderness settlement. Before the original settlers, there were pioneer scouts who surveyed these new lands and waterways. The town name of Piscataway came from these early pioneers who originally came from the town of Piscataqua. During the original land purchase, the pioneers had signed 12 Articles of Agreement with Governor Carteret, which served as the legal basis for the government of Piscataway and Woodbridge and which shaped the democratic development of self-government. In short, these articles were mainly designed to provide liberty and land ownership for new families and to allow them to establish their own government representatives and religious freedoms.